Extinct animals in the USA
- Antillean Cave Rat
- Insular Cave Rat
- Corozal Rat
- Puerto Rican Shrew
- Puerto Rican Long-nosed Bat
- Puerto Rican Long-tongued Bat
- Lesser Puerto Rican Ground Sloth
- Sherman's Pocket Gopher
- Goff's Pocket Gopher
- Tacoma Pocket Gopher
- Giant Deer Mouse
- Pallid Beach Mouse
- Gull Island Vole
- Louisiana Vole
- Puerto Rican Hutia
- Puerto Rican Paca
- Lesser Puerto Rican Agouti
- Greater Puerto Rican Agouti
- Sea Mink
- Caribbean Monk Seal
- Steller's Sea Cow
- Columbia Basin Pygmy Rabbit
- Arizona Wapiti
- Colorado Hog-nosed Skunk
- Smith Island Cottontail
- Allen's Thirteen-lined Ground Squirrel
- Banks Island Wolf
- Cascade Mountains Wolf
- Antillean Giant Rice Rat
- Eastern Elk
- Merriam's Elk
- Arizona Jaguar
- Tule Shrew
- Labrador Duck
- Heath Hen
- Spectacled Cormorant
- Atitlán Grebe
- Bermuda Night Heron
- Virgin Islands Screech-Owl
- Carolina Parakeet, Conuropsis carolinensis
- Passenger Pigeon, Ectopistes migratorius
- Guadalupe Caracara
- Bahaman Barn Owl
- Brace's Emerald
- Gould's Emerald
- Great Auk
- Grand Cayman Thrush, Turdus ravidus
- Dusky Seaside Sparrow, Ammodramus maritimus nigrescens
- Guadeloupe Burrowing Owl, Speotyto cunicularia guadeloupensis
- Guadeloupe Parakeet, Aratinga labati
- Guadeloupe Parrot, Amazona violacea
- Lesser Antillean Macaw, Ara guadeloupensis
- Cuban Red Macaw
- Martinique House Wren, Troglodytes aedon martinicensis
- Martinique Parrot, Amazona martinicana
- Slender-billed Grackle, Quiscalus palustris
- Navassa Curly-tailed Lizard
- Navassa Iguana
- Navassa Island Dwarf Boa
- Sulcate Blind Snake
- Saint Croix Racer
- Martinique Giant Ameiva, Ameiva major
- Martinique Lizard, Leiocephalus herminieri
- Ameiva cineracea
- Vegas Valley Leopard Frog
- Catahoula Salamander
- Golden Toad
- Longjaw Cisco
- Deepwater Cisco
- Lake Ontario Kiyi
- Blackfin Cisco
- Yellowfin Cutthroat Trout
- Alvord Cutthroat Trout
- Silver Trout
- Maravillas Red Shiner
- Independence Valley Tui Chub
- Thicktail Chub
- Pahranagat Spinedace
- Phantom Shiner
- Las Vegas Dace
- Grass Valley Speckled Dace
- Clear Lake Splittail
- Snake River Sucker
- Harelip Sucker
- Tecopa Pupfish
- Shoshone Pupfish
- Raycraft Ranch Killifish
- Pahrump Ranch Killifish
- Ash Meadows Killifish
- Amistad Gambusia
- San Marcos Gambusia
- Blue Walleye
- Maryland darter
- Utah Lake Sculpin
- Banff Longnose Dace
- Illinois Cave Amphipod
- Pasadena Freshwater Shrimp
- Pecatonica River Mayfly
- Robert's Stonefly
- Fort Ross Weevil
- Mono Lake Diving Beetle
- Xerces Blue
- Chestnut Ermine Moth
- American Chestnut Moth
- Phleophaga Chestnut Moth
- Central Valley Grasshopper
- Rocky Mountain Locust
- Antioch Dunes Shieldback Katydid
- Caribbean Monk Seal Nasal Mite
- Nevada Water Mite
- Passenger Pigeon Mite
- Coosa elktoe
- Carolina elktoe
- Ochlockonee arcmussel
- Recovery pearly mussel
- Arc-form pearly mussel
- Acorn pearly mussel
- Lewis pearly mussel
- Nearby pearly mussel
- Turgid-blossom pearly mussel
- Shoal sprite
- Cahaba pebblesnail
- Umbilicate pebblesnail
- Mount matafao different snail
- Short-spired elimia
- Closed elimia
- Fusiform elimia
- High-spired elimia
- Constricted elimia
- Hearty elimia
- Ribbed elimia
- Rough-lined elimia
- Pupa elimia
- Pygmy elimia
- Cobble elimia
- Puzzle elimia
- Excised slitshell
- Striate slitshell
- Pagoda slitshell
- Ribbed slitshell
- Pyramid slitshell
- Round slitshell
- Lined pocketbook
- Eelgrass limpet